Online microdosing communities have grown to the tens of thousands with more than 40,000 users subscribing to the /r/microdosing subreddit (/r/microdosing subreddit, Reddit Inc, San Francisco, CA, USA).
The number of popular media accounts and book-length treatments of microdosing has been growing. LSD, psilocybin) and has recently grown in popularity. The practice of microdosing psychedelics involves ingesting sub-hallucinogenic amounts of a psychedelic substance (e.g. This framework aims to inform researchers and clinicians as experimental microdosing research begins in earnest in the years to come.
Microdosing research complements the full-dose literature as clinical treatments are developed and neuropharmacological mechanisms are sought. The MDBC taxonomy reported here informs future research, leveraging participant reports to distil the highest-potential intervention targets so research funding can be efficiently allocated. These mixed-methods results help summarize and frame the experiences reported by an active microdosing community as high-potential avenues for future scientific research. We probe for substance-dependent differences, finding that psilocybin-only users report the benefits of microdosing were more important than other users report. We also show parallels between benefits and drawbacks and discuss the implications of these results. We describe novel findings, both in terms of beneficial outcomes, such as improved mood (26.6%) and focus (14.8%), and in terms of challenging outcomes, such as physiological discomfort (18.0%) and increased anxiety (6.7%). In the present study, we develop a codebook of microdosing benefits and challenges (MDBC) based on the qualitative reports of a real-world sample of 278 microdosers. There has been limited reporting on adverse events associated with microdosing, and the experiences of microdosers in community samples have not been categorized. According to media reports, microdosing has grown in popularity, yet the scientific literature contains minimal research on this practice. Microdosing psychedelics is the practice of consuming very low, sub-hallucinogenic doses of a psychedelic substance, such as lysergic acid diethylamide (LSD) or psilocybin-containing mushrooms.
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